·Hypertrophic Cardiomyopathy(HCM) is a disease in which the heart muscle becomes abnormally thick (hypertrophied).

·Hypertrophic Obstructive Cardiomyopathy (HOCM) – when the wall between the two bottom chambers (ventricles) of the heart become thickened, it blocks blood from flowing freely from the heart out into the body. Because of this, patients with HOCM experience difficulties in their daily lives such as breathing difficulties.

·Nonobstructive Hypertrophic Cardiomyopathy – when the left ventricle itself becomes thickened and stiff as a result of HCM, it can make it harder for the ventricle to fill with enough blood to pump out into the body. In some cases, the Mitral valve leaflet is pulled towards LVOT, resulting in Mitral valve regurgitation.

·HCM is affecting 1 in 200 to 300. Therefore we can estimate HCM is present in nearly over 1 million in the U.S. and 36 million or more worldwide.

·For the mild HOCM, medications like beta-blockade are used. And for sever HOCM, a surgical treatment (septal myectomy) or alcohol septal ablation is treated. Alcohol septal ablation is a percutaneous technique that involves injection of alcohol into the septal, however, not that precise in targeting the ablation site.